CIMZIA is for adults only.
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In a clinical trial, more patients who responded and continued on CIMZIA versus placebo showed noticeable improvement in signs and symptoms of moderate to severe Crohn's disease at 26 weeks. Nearly half of those patients who continued to take CIMZIA were in remission at 26 weeks.

If your doctor has recently prescribed CIMZIA, you may have questions. Get the information and support you need for a smooth transition into treatment with CIMZIA:

Things to know before starting CIMZIA Crohn's disease treatment

Because it affects your immune system, CIMZIA can make you more susceptible to infection. You should not start CIMZIA if you have an infection or are being treated for an infection.

Before starting CIMZIA, tell your doctor about all of your medical conditions, including if you:

  • Think you have an infection. You should not start taking CIMZIA if you have any kind of infection.
  • Are being treated for an infection
  • Have signs of an infection, such as a fever, cough, or flu-like symptoms
  • Have any open cuts or sores on your body
  • Get a lot of infections or have infections that keep coming back
  • Have diabetes
  • Have HIV
  • Have TB, or have been in close contact with someone with TB
  • Were born in, lived in, or traveled to countries where there is more risk of getting TB. Ask your doctor if you are not sure.
  • Live or lived in certain parts of the country (such as the Ohio and Mississippi River valleys) where there is an increased risk for getting certain kinds of fungal infections (histoplasmosis, coccidioidomycosis, blastomycosis). These infections may develop or become severe if you take CIMZIA. If you do not know if you have lived in these types of areas, ask your doctor.
  • Have or have had hepatitis B
  • Have or have had any type of cancer
  • Have congestive heart failure
  • Have seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis
  • Are scheduled to receive a vaccine. Do not receive a live vaccine while taking CIMZIA.
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Are allergic to any of the ingredients in CIMZIA
  • Are taking any medicines, including prescription and nonprescription medicines, vitamins, and herbal supplements. Your doctor will tell you if it is okay to take your other medicines while taking CIMZIA.
  • Especially tell your doctor if you take:
    • Kineret® (anakinra), Orencia® (abatacept), Rituxan® (rituximab), Tysabri® (natalizumab). You have a higher chance for serious infections when taking CIMZIA with these medicines.
    • A TNF blocker: Remicade® (infliximab), Humira® (adalimumab), Enbrel® (etanercept) or Simponi® (golimumab)

    You should not take CIMZIA while you take one of these medicines.

While taking CIMZIA:

  • Your doctor should watch for signs or symptoms of TB
  • You should not receive a live vaccine
  • Call your doctor right away if you get an infection or any symptoms of an infection, or if you have any open cuts or sores

Before starting CIMZIA, tell your doctor about all of your medical conditions as well as all the medicines you take. Be sure to include prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take: Kineret® (anakinra), Orencia® (abatacept), Rituxan® (rituximab), or Tysabri® (natalizumab). You have a higher chance for serious infections when taking CIMZIA with these medicines. You should not take CIMZIA while you take one of these medicines.

After starting CIMZIA, if you get an infection, any sign of an infection including a fever, cough, flu-like symptoms, or have open cuts or sores on your body, call your doctor right away. CIMZIA can make you more likely to get infections or make any infection that you may have worse. Patients 65 years of age or older, patients with other long-term medical conditions, or taking certain other drugs that affect the immune system, such as corticosteroids or methotrexate, may be at a greater risk of infection.

Also tell your doctor if you are taking a tumor necrosis factor (TNF) blocker such as Remicade® (infliximab), Humira® (adalimumab), Enbrel® (etanercept), or Simponi® (golimumab). You should not take CIMZIA while you take one of these medicines.

Serious infections have happened in patients taking CIMZIA, including tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Please read the CIMZIA Important Safety Information for additional information on CIMZIA and discuss it with your doctor.

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