The recommended loading dose of CIMZIA® (certolizumab pegol) for adults with moderate to severe CD is 400 mg (given as 2 subcutaneous injections of 200 mg) initially and at weeks 2 and 4. In patients who obtain a clinical response, the recommended maintenance regimen is 400 mg every 4 weeks.

Important Safety Consideration
Anaphylaxis or serious allergic reactions may occur. Some of these reactions occurred after the first administration of CIMZIA. Hypersensitivity reactions have been reported rarely following CIMZIA administration.

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