Recommended loading dosing

The loading phase of CIMZIA treatment for moderate to severe rheumatoid arthritis (RA) consists of the first 3 doses. During the loading phase, the recommended dose of CIMZIA for adults with RA is 400 mg initially followed by 400 mg again at week 2 and week 4.1 A 400-mg dose requires administration of 2 subcutaneous injections of 200 mg; the injections should occur at separate sites in the thigh or abdomen.1

Recommended maintenance dosing

After the loading dose (per above), follow with 200 mg every other week. For maintenance dosing, CIMZIA 400 mg every 4 weeks can be considered.1 A 400-mg dose requires administration of 2 subcutaneous injections of 200 mg each; the injections should occur at separate sites in the thigh or abdomen.1



Important Safety Information


Concurrent administration of CIMZIA with certain biological DMARDs, including anakinra, abatacept, and rituximab, is not recommended due to an increased risk of serious infections.

Anaphylaxis or serious allergic reactions may occur. Hypersensitivity reactions have been reported rarely following CIMZIA administration.

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