CIMZIA: FDA-approved for more than a decade

Studied in over 80 clinical trials across all approved indications, CIMZIA has a
history of clinical use.*

*Includes approved indications for RA, CD, PsA, AS, PsO, and nr-axSpA as well as other completed
and ongoing research.

See information about serious side effects and common side effects below.

The following side effects were most commonly seen during the CIMZIA clinical trials in Crohn's disease. These are not all the possible side effects that may happen with CIMZIA use. Always discuss the risks versus benefits of therapy with your doctor, and be sure to mention any side effects you experience.

CIMZIA is the longest-studied biologic for safety in Crohn’s disease, at 7 years

During clinical studies for CIMZIA in Crohn's disease, the most common side effects were:

  • Upper respiratory infections in 20% of CIMZIA-treated patients vs. 13% of placebo patients
  • Urinary tract infections in 7% of CIMZIA-treated patients vs. 6% of placebo patients
  • Arthritis pain in 6% of CIMZIA-treated patients vs 4% of placebo patients

Risk of Serious Side Effects

CIMZIA is an anti-tumor necrosis factor (TNF) biologic, which can lower the ability of your immune system to fight infections. Some people who received CIMZIA have developed serious infections, including tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some of these serious infections have caused hospitalization and death. Your healthcare provider should test you for TB before starting CIMZIA.

Stop using CIMZIA, and tell your healthcare provider right away if you think you have an infection or have symptoms of an infection. Certain potentially fatal infections and cancers, including lymphoma, have occurred in people who received anti-TNF therapy.

For people who receive TNF blockers, including CIMZIA, the chances of getting certain types of cancers may increase. Some people who receive TNF blockers, including CIMZIA, have developed a rare type of cancer which may cause death, called hepatosplenic T-cell lymphoma. Some people who receive CIMZIA have developed certain types of skin cancer.

Other Serious Side Effects

  • Heart failure, including new or worsening heart failure
  • Allergic reactions
  • Hepatitis B virus reactivation in people who carry the virus
  • New or worsening nervous system problems
  • Blood problems
  • Immune reactions, including a lupus-like syndrome

Common Side Effects of CIMZIA

While results may vary, and every person taking CIMZIA is different, the most common side effects of CIMZIA include:

  • Upper respiratory infections (flu, cold)
  • Rash
  • Urinary tract infections (bladder infections)

These are not all the possible side effects of CIMZIA. For more information or medical advice about side effects, talk to your gastroenterologist.

Visit, or call 1-800-FDA-1088 to reach the FDA

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

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