Dosing Injections at Home

ANNOUNCER:

00:00:08

Welcome. You’ve taken a big step in treating your condition by seeing your healthcare provider and getting a prescription for CIMZIA. Now, before attempting to self-inject, please watch this instructional video in its entirety. For your protection, it’s important that you carefully follow its instructions. Also, read the Important Safety Information and refer to the accompanying medication guide.

00:00:32

Remember, as with any medication, CIMZIA must be taken as directed by your healthcare provider. So we’d like to remind you not to miss any injections of CIMZIA. If you miss a dose, call your healthcare provider or pharmacist for instructions.

00:00:47

Make sure your healthcare provider shows you how to inject CIMZIA before you do it yourself. A friend or relative can also help after they have been trained in giving injections.

These instructions do not take the place of talking with your healthcare provider about your medical condition or treatment. These instructions are for 1 injection only. You may need more than 1 injection at a time depending on your prescribed dose of CIMZIA.

And remember, always keep CIMZIA, injection supplies, and all other medications out of the reach of children.

If you have any questions at all about CIMZIA or how to take your medication, make sure to call your healthcare provider or call us at 1-866-4-CIMZIA.

ERICA:

00:01:29

Hi, I’m Erica and I’m going to show you how to inject your medication.

00:01:40

Each CIMZIA prefilled syringe package comes with:

• 2 glass prefilled syringes of CIMZIA, each with a fixed needle, 2 alcohol swabs, a medication guide, and full prescribing information

For each injection you will use:

• 1 prefilled syringe of CIMZIA with needle, 1 alcohol swab. You will also need 1 clean cotton ball or gauze pads, and a puncture-proof container for disposing of used needles and syringes.

These are not included in the CIMZIA prefilled syringe package, so if you do not have all the supplies you need, talk to your pharmacist.

00:02:25

Take your syringe package containing CIMZIA from the refrigerator. Remember, each prefilled syringe contains one 200-milligram injection. Your doctor will tell you what your CIMZIA dose is.

00:02:40

First, make sure the name “CIMZIA” appears on the dose tray and the syringe label and that the packaging and seals aren’t broken or missing.

Check the expiration date on the syringe. Also, check to make sure that the liquid in the syringe is clear and colorless to yellow and free from particles. Do not inject the medicine if it is cloudy, discolored or contains particles. Each prefilled syringe contains 200 mg, the right dose of medicine for one injection. If you are prescribed to take 400 mg of CIMZIA, you will need to use two CIMZIA prefilled syringes to take two injections. Take either one or two CIMZIA prefilled syringes and alcohol swabs for injection, depending on your prescribed dose.

If there is still a prefilled syringe in the carton, put it back in the refrigerator right away. Let the medicine in the syringe come to room temperature before injection. This will take about 30 minutes.

00:03:46

Okay, now we’re going to inject CIMZIA.

Before you start, wash your hands.

CIMZIA may be injected into your abdomen or upper thigh area. If you are prescribed to take more than one injection, each injection should be given at a different injection site, in your abdomen and upper thigh. Each new injection should be given at least one inch from a site you used before. If you choose the abdomen, avoid the 2 inches around your navel.

00:04:17

Do not inject into areas where the skin is tender, bruised, red or hard or where you have scars or stretch marks. Change injection sites between your abdomen and upper thighs to reduce the risk of reaction.

You may find it helpful to keep notes on the locations of injection sites you use. Use an alcohol swab to wipe over the site where you will inject CIMZIA. Do not touch the clean area again until you are ready for the injection.

00:04:54

Now we’re ready to inject. Hold the syringe so the needle is pointing up. You may see air bubbles. This is normal. There is no need to remove air bubbles before giving your injection. Injecting the solution with air bubbles will not harm you.

Remove the plastic ring needle cover by pulling straight up on the plastic ring. Take care not to touch the needle and do not allow the needle to touch any surface. Do not bend the needle. Place the needle cover to the side.

Hold the syringe with the needle facing down, like this. Gently pinch a fold of the cleaned area of skin. Insert the needle at about a 45° angle with a quick, short, “dart-like” motion, like this. Release the skin pinch, keeping the syringe in position. Inject under the skin all of the medicine in the prefilled syringe. When the syringe is empty, remove the needle from the skin and press the clean cotton ball or gauze pad over the injection site for 10 seconds. Do not rub the injection site. You may have a slight amount of bleeding. This is normal. To avoid needle-stick injury, do not try to recap the needle.

00:06:11

Next, we’ll talk about the right way to dispose of your syringe. Before you start injecting CIMZIA, check with your doctor’s office for instructions on how to properly dispose of syringes. Each state or town may have different requirements for disposing of used syringes.

ANNOUNCER
For more information about safe sharps disposal, and for specific information about sharps disposal in the state in which you live, go to the FDA’s website at: www.fda.gov/safesharpsdisposal.

PATIENT
Ask your doctor or pharmacist how to get a puncture-proof, sharps container that meets the requirements of your particular state or town. When the container is about two-thirds full, tape the lid closed, and dispose of it as instructed by your doctor, nurse or pharmacist. Do not throw it away in the trash or recycling. Alcohol swabs may be placed in the trash unless you are instructed otherwise.

ANNOUNCER
If you do not have an FDA-cleared sharps disposal container, you may use household container that is: Made of a heavy-duty plastic, can be closed with a tightfitting puncture-resistant lid, without sharps being able to come out, is upright and stable during use, is leak-resistant, and is properly labeled to warn of hazardous waste inside the container