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UCBCares® 1-844-599-CARE (2273)

This site is intended for US residents.
UCBCares® 1-844-599-CARE

Crohn's disease overview

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Crohn's disease (CD) belongs to a group of conditions known as inflammatory bowel diseases (IBD). CD is a chronic inflammatory condition of the gastrointestinal (GI) tract, affecting as many as 700,000 Americans. It strikes about the same number of men as women, and, while it can occur at any age, it's more prevalent among adolescents and young adults between the ages of 15 and 35. It also tends to run in families.

The exact causes of CD are not known, but recent research suggests hereditary, genetic, or environmental factors can contribute to its development.

CD is considered an immune disorder. When you have CD, your immune system may produce too much of a protein called tumor necrosis factor (TNF). TNF may activate the immune system, causing inflammation in the gastrointestinal tract.


What are its symptoms?

CD can affect any part of the GI tract. While symptoms vary from patient to patient, the more prominent symptoms of CD include:

  • Persistent diarrhea

  • Rectal bleeding

  • Urgent need to move bowels

  • Abdominal cramps and pain

  • Sensation of incomplete evacuation

  • Constipation (which can lead to bowel obstruction)

Other symptoms associated with CD include:

  • Fever

  • Loss of appetite

  • Weight loss

  • Fatigue

  • Night sweats

  • Loss of normal menstrual cycle

Living with Crohn's disease

CD is a chronic disease, and typically patients go through periods when their condition flares up and causes symptoms, followed by periods of remission with no noticeable symptoms at all.


Are my Crohn's disease symptoms being well controlled?

Degrees of relief and treatment results vary from patient to patient. Only you can determine if you are getting the symptom relief you had hoped for. With time, many patients learn to cope with their symptoms even though those symptoms may be worsening. And what worked at one stage of your disease may not work at another.

As long as active disease is present, you will continue to experience flare-ups and risk further damage to your GI tract. Plus, the longer your CD remains active, the more likely it is that you will need surgery. That's why talking to your doctor regularly about your symptoms is an important part of managing your disease.

Prior to your visit, consider how you'd answer these questions:

  • When were you first diagnosed?

  • What treatments have you received?

  • What symptoms are you experiencing now?

  • Do your symptoms still seem to be getting worse?

  • What other treatments might you consider?

  • Is CIMZIA® (certolizumab pegol) an option for you?

Having answers to these questions can lead to a more productive conversation with your doctor.

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aEligibility: Not valid for prescriptions that are reimbursed, in whole or in part, under Medicare (including Medicare Part D), Medicaid, similar federal- or state-funded programs (including any state prescription drug assistance programs and the Government Health Insurance Plan available in Puerto Rico), or where otherwise prohibited by law. Product dispensed pursuant to program rules and federal and state laws. Claims should not be submitted to any public payor (ie, Medicare, Medicaid, Medigap, Tricare, VA, and DoD) for reimbursement. Patients and pharmacists are responsible for notifying insurance carriers or any other third party who pays for or reimburses any part of the prescription filled using this card as may be required by the insurance carrier's terms and conditions and applicable law. The maximum annual benefit amount is $11,000 per calendar year. The parties reserve the right to amend or end this program at any time without notice.

bThe CIMplicity program is provided as a service of UCB and is intended to support the appropriate use of CIMZIA. The CIMplicity program may be amended or cancelled at any time without notice. Some program and eligibility restrictions may apply.

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