How CIMZIA Works For You

Learn How CIMZIA Can Help

FOR Non-Radiographic Axial Spondyloarthritis

While some pain relievers provide temporary relief for your symptoms of non-radiographic axial spondyloarthritis (nr-axSpA), they don’t all address the underlying cause of the disease. ClMZIA is the first and only therapy of its kind for nr-axSpA* and is proven to improve symptoms and disease activity over time.

*CIMZIA is an anti-tumor necrosis factor (TNF) biologic.

What’s Possible With CIMZIA?

See the results from a clinical trial in patients who took CIMZIA:

Improved Symptoms

Nearly 5 out of 10 people taking CIMZIA had major improvement in disease activity, including back pain, stiffness, and joint swelling at 1 year—some saw results in as fast as 2 weeks.

47% of CIMZIA patients at 1 year vs. 7% of placebo patients; 21% of CIMZIA patients at 2 weeks vs. 1% of placebo patients. Patients were allowed to use additional medications for their nr-axSpA.

Less Spinal Pain

People taking CIMZIA had 33% less back pain than placebo-treated patients did at week 12.

Improved Quality of Life

People taking CIMZIA reported improvement in their quality of life, such as the ability to engage in daily and social activities, at 12 weeks.

5.0-point improvement in CIMZIA patients vs. 1.5-point in placebo patients at week 12.

Improved Physical Function

People taking CIMZIA had a 41% improvement in their physical function—such as bending, reaching, and climbing stairs—at 12 weeks, and had a 50% improvement at 1 year.§

§CIMZIA results at week 12 and at 1 year compared with 9% and 13%, respectively, in placebo-treated patients.

Patients on CIMZIA experienced these results during a clinical trial. Results shown above are based on a dose of 200 mg every 2 weeks plus other non-biologic treatment or placebo plus other non-biologic treatment. Results may vary, every person taking CIMZIA is different and responds differently to therapy.

Long-Term Results

Nearly 4 out of 10 people who continued taking CIMZIA experienced improvement in disease activity, including back pain, stiffness, and joint swelling at 3 years.

Patients who stayed on CIMZIA for 3 years reported improvements in spinal pain, quality of life, and physical function.

37% of CIMZIA patients at week 156.

Longer-term results are based on data from patients who stayed on CIMZIA for 3 years. After 1 year, patients and doctors knew that CIMZIA was being used, which may have affected these results.

Did You Know?

Did you know that many nr-axSpA symptoms are the same as ankylosing spondylitis (AS)? Learn more about AS and how CIMZIA can help if you’ve been diagnosed.

Beth and Brandy

Hear From Real CIMZIA Patients

Dealing with nr-axSpA can be a lonely experience. But you’re not alone. Hear from actual patients as they share their stories about dealing with painful nr-axSpA symptoms and how CIMZIA helped them in their journey.

Individual results may vary.

The Logic of a Biologic Like CIMZIA

CIMZIA is a biologic. A biologic is a drug that comes from living sources. As an anti-tumor necrosis factor (TNF) biologic, CIMZIA works to block the extra TNF that leads to inflammatory pain. Learn more about TNF and why an anti-TNF may be the right treatment for nr‑axSpA symptoms.

Free to Move About Your Day

What does it mean to feel free to move about your day? If your day-to-day routine has been affected by nr-axSpA, something as simple as getting out of the bed in the morning with less stiffness or back pain can make a difference.

People taking CIMZIA saw an improvement at week 12 and at 1 year in swelling and tenderness where tendons and ligaments attach to bones.

2.1-point improvement in CIMZIA patients vs. 0.4-point in placebo patients at week 12 and 2.7-point improvement in CIMZIA patients vs. 0.5-point in placebo patients at 1 year. Based on a tool that measures inflammation.

Finding a non-radiographic axial spondyloarthritis medicine that works for you could also mean feeling more productive in the workplace. Based on a survey, patients reported improved work productivity at week 12 and at 1 year.** These patients felt that their symptoms were getting in the way less while they were at work in the last month. Individual results may vary.

**2.2-point improvement in CIMZIA patients vs. 0.6-point in placebo patients at week 12 and 3.5-point improvement in CIMZIA patients vs. 1.3-point in placebo patients at 1 year.

Kids Playing

It’s time to get back to the things you love without nr-axSpA holding you back. When talking to your doctor about your non-radiographic axial spondyloarthritis treatment options, ask if CIMZIA could work for you.


The CIMZIA doctor discussion guide is available for download to assist with your next conversation with your rheumatologist

How Disruptive Is Your Inflammatory Back Pain?

If your back pain has lasted 3 months or longer and worsens with rest, you may have inflammation caused by nr-axSpA.

Fill out our discussion guide and share with your specialist to help assess the effect your condition is having on your day-to-day life.