How CIMZIA Works For You

Learn How CIMZIA Can Help

FOR Non-Radiographic Axial Spondyloarthritis

While some pain relievers provide temporary relief for your symptoms of non-radiographic axial spondyloarthritis (nr-axSpA), they don’t all address the underlying cause of the disease. ClMZIA is the first and only therapy of its kind for nr-axSpA* and is proven to improve symptoms and disease activity over time.

*CIMZIA is an anti-tumor necrosis factor (TNF) biologic.

What’s possible with CIMZIA?

See the results from a clinical trial in patients who took CIMZIA:

Improved Symptoms

Nearly 5 out of 10 people taking CIMZIA had major improvement in disease activity at 52 weeks—for some in as fast as 2 weeks.

47% of CIMZIA patients at 52 weeks vs. 7% of placebo patients; 21% of CIMZIA patients at 2 weeks vs. 1% of placebo patients. Based on a tool that measures disease activity such as back pain, stiffness, and joint swelling.

Less Spinal Pain

People taking CIMZIA had 33% less back pain than placebo-treated patients at week 12.

Improved Quality of Life

People taking CIMZIA reported improvement in their quality of life at 12 weeks.

5.0-point improvement in CIMZIA patients vs. 1.5-point in placebo patients at week 12. Based on a tool that measures quality of life such as daily and social activities.

Improved Physical Function

People taking CIMZIA had a 41% improvement in their physical function at 12 weeks and 50% improvement at 1 year.§

§CIMZIA patients had a 41% and 50% reduction in physical disability at week 12 and 1 year vs 9% and 13% of placebo patients, respectively. Based on a tool that measures physical function such as bending, reaching, and climbing stairs.

In a clinical trial, patients on CIMZIA experienced these results. Results shown above are based on a dose of 200 mg every 2 weeks PLUS other non-biologic treatment or placebo PLUS other non-biologic treatment. Results may vary; every person taking CIMZIA is different and responds differently to therapy.

Did you know that many nr-axSpA symptoms are the same as ankylosing spondylitits (AS)?
Learn more about AS and how CIMZIA can help if you’ve been diagnosed.

The Logic of a Biologic Like CIMZIA

CIMZIA is a biologic, meaning it is a drug that is derived from living sources. As an anti-tumor necrosis factor (TNF) biologic, CIMZIA works to block the extra TNF that leads to inflammatory pain. Learn more about TNF and why an anti-TNF may be the most appropriate treatment for nr-axSpA symptoms.

Free to Move About Your Day

What does it mean to feel free to move about your day? If your day-to-day routine has been affected by nr-axSpA, something as simple as getting out of the bed in the morning with less stiffness or back pain can make a difference.

People taking CIMZIA saw an improvement in swelling and tenderness where tendons and ligaments attach to bones, at week 12 and week 52.||

||2.1-point improvement in CIMZIA patients vs. 0.4-point in placebo patients at week 12 and 2.7-point improvement in CIMZIA patients vs. 0.5-point in placebo patients at week 52. Based on a tool that measures inflammation.

It could also mean feeling more productive at work. Based on a survey, patients reported improved work productivity at week 12 and week 52. These patients felt that their symptoms were getting in the way less while they were at work in the last month. Individual results may vary.

2.2-point improvement in CIMZIA patients vs. 0.6-point in placebo patients at week 12 and 3.5-point improvement in CIMZIA patients vs. 1.3-point in placebo patients at week 52 (nominal p-value vs. placebo).

Kids Playing

It’s time to get back to the things you love without nr-axSpA holding you back. Ask your doctor about CIMZIA to see if it could be right for getting you back to feeling like yourself again.

The CIMZIA doctor discussion guide is available for download to assist with your next conversation with your rheumatologist

How Disruptive Is Your Inflammatory Back Pain?

Let's take a look at how you're managing your symptoms. If your back pain has lasted 3 months or longer and worsens with rest, you may have inflammation caused by non-radiographic axial spondyloarthritis.